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  1. Allosteric regulation - Wikipedia

    PFK can be allosterically inhibited by high levels of ATP within the cell. When ATP levels are high, ATP will bind to an allosteric site on phosphofructokinase, causing a change in the enzyme's three …

  2. ALLOSTERIC Definition & Meaning - Merriam-Webster

    The meaning of ALLOSTERIC is of, relating to, undergoing, or being a change in the shape and activity of a protein (such as an enzyme) that results from combination with another substance at a point …

  3. What is allosteric regulation? Exploring the exceptions that prove the ...

    “Allosteric” was first introduced to mean the other site (i.e., a site distinct from the active or orthosteric site), an adjective for “regulation” to imply a regulatory outcome resulting from ligand binding at …

  4. Allosteric Regulation - an overview | ScienceDirect Topics

    Allosteric regulation is classically defined as action at a distance, where a perturbation outside of a protein active site affects function.

  5. Allostery: A Key Mechanism in Biology and Medicine

    Jul 27, 2025 · Allostery describes a fundamental regulatory process in biological systems where a molecule binding at one site on a protein influences the activity or binding affinity at a different, often …

  6. Allostery | Quarterly Reviews of Biophysics | Cambridge Core

    Jan 24, 2025 · Allostery describes the ability of biological macromolecules to transmit signals spatially through the molecule from an allosteric site – a site that is distinct from orthosteric binding sites of …

  7. 1.18: Enzymes and Allosteric Regulation - Biology LibreTexts

    Inhibition and activation of enzymes via other molecules are important ways that enzymes are regulated. Inhibitors can act competitively or noncompetitively; noncompetitive inhibitors are usually allosteric …

  8. ALLOSTERIC Definition & Meaning | Dictionary.com

    Allosteric definition: pertaining to regulation of the rate of an enzymatic process.. See examples of ALLOSTERIC used in a sentence.

  9. What is allosteric regulation? Exploring the exceptions that prove the ...

    Jan 23, 2024 · “Allosteric” was first introduced to mean the other site (i.e., a site distinct from the active or orthosteric site), an adjective for “regulation” to imply a regulatory outcome resulting from ligand …

  10. Allostery Beyond Amplification: Temporal Regulation of Signaling ...

    16 hours ago · By computing the mutual information between an allosterically modulated upstream enzyme and a downstream signaling protein activated by its product, we show that allostery controls …