Sam Farmer makes his picks and score predictions for Week 12 of the NFL season, with Patrick Mahomes and the Chiefs winning at home over the Colts.

Check out our NFL Week 12 picks for the 14 NFL games this week, a week that begins with the Buffalo Bills at Houston Texans on Thursday Night Football on Nov. 20 and ends with the Carolina Panthers at San Francisco 49ers on Monday Night Football on Nov. 24.

Welcome to the Thursday edition of the Pick Six newsletter! We are exactly ONE WEEK away from Thanksgiving, and we have a lot to be thankful for tonight we get to watch Josh Allen play, and let me just say, there is no one in the NFL better at playing ...

#Falcons QB Michael Penix Jr does, in fact, need surgery to repair his ACL, with 9 months of recovery, at least, coming. He’s sought the opinion of experts, including from Dr. Neal ElAttrache. Penix has an ACL sprain, but full reconstruction is needed. pic.twitter.com/rdz34X1eAh

The Week 12 NFL schedule for the 2025 season brings some exciting matchups. The Chiefs hope to get their season back on track against the Colts, historical nemesisAaron Rodgerscould make his return to Chicago, and two of the league's most exciting offenses ...

Each pick has a confidence level of 1-10, with 10 being the most confident. For more information on the pick methodology, check out the Week 1 edition of this series. Keep in mind that since the idea here is to make high-percentage plays,

Experts from around the NFL make their picks for a Week 17 game between the New York Giants and Las Vegas Raiders.