In 1985, the Nobel Prize in Physiology or Medicine was awarded to Michael Brown and Joseph Goldstein for identifying the receptor that clears LDL particles from the bloodstream. High blood levels of ...

Senior Author: Paul A. Slesinger, PhD, Lillian and Henry M. Stratton Professor of Neuroscience and Director of the Center for Neurotechnology and Behavior, Icahn School of Medicine at Mount Sinai, New ...

Leg pain, numbness, coldness, swelling, and skin changes, especially at night, can signal high LDL cholesterol. These ...

Synuclein (α-Syn) is a presynaptic protein primarily associated with Parkinson’s disease and other neurodegenerative diseases ...

Cholesterol refers to a diverse group of fats that serve a number of necessary functions in the body. Cholesterol helps keep cells from freezing, helps absorb fat soluble vitamins, serves as an ...

Chemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic diseases such as obesity and diabetes. In addition, it plays a critical role ...

High cholesterol, or hypercholesterolemia, affects nearly 1 in 3 American adults—yet it often goes undetected until a serious event like a heart attack or stroke occurs. It's one of the major ...