Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...
Oocytes are among the longest-lived cells. Scientists have been trying to understand what enables such longevity, because oocytes—like other nondividing, long-lasting cells—have a high risk of ...
Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...
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