Huntington’s Disease is a hideous progressive disease. One of the primary causes is a mutant protein called mhTT, which is a corrupted essential protein in spinal fluid. mhTT replaces the proper ...

Huntington disease (HD) is an incurable, inherited neurological disorder caused by the mutant Huntingtin gene, which produces a mutant form of Huntingtin protein (mHTT). In addition to creating the ...

The potential of genome-editing techniques, such as CRISPR/Cas9, to alleviate disease burden has ignited the imagination for thousands of researchers looking for new therapeutic strategies. Scientists ...

A Chinese study led by researchers at Fudan University in Shanghai has described a novel strategy to target the 'undruggable' mutant Huntingtin (mHTT) protein by screening for compounds that directly ...

~ Treatment generally well-tolerated with no significant safety issues related to AMT-130 in treated patients through one year of follow-up ~ ~ A mean reduction of 53.8% of mutant HTT (mHTT) observed ...

Restricting food intake to a specific time period each day could benefit people living with Huntington’s disease, a new study indicates. Share on Pinterest Restricting food intake to the same 6-hour ...

In a new study published in the Brain as cover story, the joint research group of Prof. Xi Chen from Nanjing University and Prof. Zhong Pei from Sun Yat-sen University reports “Therapeutic reversal of ...

BOSTON, Sept. 17, 2025 /PRNewswire/ -- Skyhawk Therapeutics, Inc., a clinical-stage biotechnology company developing novel small molecule therapies designed to modulate critical RNA targets, today ...

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease. Its characteristic features include mental deterioration, psychiatric disorder and motor dysfunction, primarily chorea, an ...