The structure of a key part of the machinery that allows cells to divide has been identified by researchers, opening new possibilities for throwing a wrench in the machine and blocking runaway cell ...
For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...
Crystal structures of the molecular motor kinesin show conformational variability in a structural element called the neck linker. Conformational change in the neck linker, initiated by ATP exchange, ...
The structure of a key part of the machinery that allows cells to divide has now been identified by a team of researchers. "The structure of kinesin-5 is unexpected, and the implications are big -- it ...
Learn more about an important cellular protein called kinesin from this video by the University of California San Francisco (UCSF), and Ron Vale Ph.D., a UCSF researcher. Kinesin is a motor protein, ...
Kinesin-5 plays a crucial role in cell division by allow microfilaments to slide past each other. The kinesin-5 structure shows a central rod connecting two motor units that walk along microfilaments ...
Inside mammalian cells, kinesin plays the same role as do trucks and locomotives within our countries: it is the main driving force behind the transport of manufactured goods. No wheels are involved, ...
One of the hallmarks of cancer is the uncontrolled growth of cells that leads to tumours forming. Using chemotherapy that disrupts the machinery needed for cell division is commonly used to tackle ...
The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis -- opening new possibilities for throwing a wrench in ...