In the genome, genes that code for protein are often divided into sections called exons, which are separated by spacers called introns. When a region of DNA is transcribed into messenger RNA (mRNA) or ...

While recent studies have identified higher than anticipated heterogeneity of mutation rate across genomic regions, mutations in exons and introns are assumed to be generated at the same rate. Here we ...

Researchers have shown for the first time that non-coding parts of genes called introns can copy themselves and move around the genome. Nevertheless, these DNA sequences remain mysterious. Scientific ...

One of the most long-standing, fundamental mysteries of biology surrounds the poorly understood origins of introns. Introns are segments of noncoding DNA that must be removed from the genetic code ...

Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor Protein-coding genes carry the blueprint for protein production. In higher ...

Researchers have developed a technique to capture rapidly evolving genomic regions to understand evolutionary relationships among closely related species. Typically, studies use protein-coding genes, ...

Each mRNA transcript contains coding regions, known as exons, and noncoding regions, known as introns. They also include sites that act as signals for where splicing should occur, allowing the cell to ...

Watching fruit flies buzz around the ripe bananas in your kitchen, you might think it’s a tad ludicrous, mortifying even, that humans have a similar number of genes—about 23,000—as the lowly insects.

Researchers at Baylor College of Medicine and collaborating institutions have discovered that a protein called hnRNPM helps protect the integrity of the process cells use to make proteins. The protein ...

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work. As you sit and read, they are faithfully ...

Researchers at Baylor College of Medicine and collaborating institutions have discovered that a protein called hnRNPM helps protect the integrity of the process cells use to make proteins. hnRNPM ...