Pharmaceutical Separation Science Session Day two of HPLC 2025 concluded with a session on pharmaceutical separations chaired ...

In the past few years, high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) has matured to a true alternative to antibody-based immunoassays in routine therapeutic drug ...

HPLC-MS analysis identified hundreds of components in Androctonus scorpion venoms, with disulfide-rich peptides being abundant. All three scorpion venoms exhibited hyaluronidase activity, while ...

What’s the difference between High Performance Liquid Chromatography (HPLC) and Ion Chromatography (IC)? What are the capabilities and limitations of each technique? Knowing these differences can ...

As analytical technology continues to advance, both regulatory agencies and pharmaceutical companies are keen to avail themselves of these enhancements. In the case of chromatography, evolution from ...

When conducting reproducible and interference-free analysis by liquid chromatography, the purity of the solvents used, particularly the purity of water, is crucial for the sensitivity of this method, ...

High-performance liquid chromatography (HPLC) gives chemists access to a world of knowledge about molecules both large and small. When combined with high-resolution detection methods such as mass ...

Investigation of peak purity failure during HPLC method validation led to discovery of a co-eluting impurity under the main peak. Spectral analysis, including three-dimensional modelling, was used to ...

As candidate oligonucleotide therapeutics move through the drug-development path past compound synthesis and in vitro testing, there has been an increasing need to understand how such compounds behave ...