Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...
There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...
New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their ...
Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...
Understanding how regulatory T cells (Tregs) develop and work is key to determining how they might be manipulated to encourage the destruction of cancer cells or prevent autoimmunity. Cell behavior is ...
Scientists capture the most detailed 3D images of chromatin condensates, revealing how DNA packs tightly inside cells.
Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...
A team led by HHMI Investigator Michael Rosen used advanced imaging techniques to understand how fibers of compacted DNA and proteins are organized and interact inside membrane-less, droplet-like ...
Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions.